There are a host of troubling facts about adverse reactions to wine. The FDA determined long ago that about 1% of the population is allergic to sulfites, and many more people sensitive to it in varying degrees. Scientists also found that sweet white wines typically have more sulfites than red wines. And yet, curiously, more people complain of headaches from red wine than whites. Also, dried fruits commonly contain sulfites - but nobody’s laid low by a "dried fruit headache."
Some experts believe that tannins, from the grape skins, could be a cause. Tannins release serotonin, a neurotransmitter. However, tannins also are found in chocolate, soy and tea. So why don't we hear about tofu headaches?